Kolb B, Nonneman A J
Science. 1976 Jul 23;193(4250):335-6. doi: 10.1126/science.935872.
Bilateral removal of the sulcal prefrontal cortex in rats at 60 days of age and older results in aphagia and adipsia, but removal of this area before 60 days of age does not affect food or water regulation. Apparently the development of the role of this neocortical region in feeding and drinking continues well beyond the time of weaning in the rat.
对60日龄及以上的大鼠双侧切除沟状前额叶皮质会导致摄食和饮水障碍,但在60日龄之前切除该区域不会影响食物或水分调节。显然,在大鼠中,这个新皮质区域在进食和饮水方面所起作用的发育在断奶之后仍会持续很长时间。