Tjhie J H, van de Putte E M, Haasnoot K, van den Brule A J, Vandenbroucke-Grauls C M
Department of Clinical Microbiology, University Hospital Vrye Universiteit, Amsterdam, The Netherlands.
Scand J Infect Dis. 1997;29(4):424-5. doi: 10.3109/00365549709011844.
A case of fatal encephalitis in a 9-year-old girl is described. Serology showed high titre antibodies against Mycoplasma pneumoniae. In addition M. pneumoniae was detected in cerebrospinal fluid by polymerase chain reaction. Direct invasion of the central nervous system as opposed to a secondary immunologic reaction to a M. pneumoniae infection of the respiratory tract in the pathogenesis of encephalitis is discussed.
描述了一名9岁女孩致命性脑炎的病例。血清学检查显示抗肺炎支原体抗体滴度很高。此外,通过聚合酶链反应在脑脊液中检测到肺炎支原体。讨论了在脑炎发病机制中,是肺炎支原体直接侵入中枢神经系统,而非对呼吸道肺炎支原体感染的继发免疫反应。