镓-67在恶性外耳道炎抗生素治疗反应评估中的应用——病例报告

Use of gallium-67 in the assessment of response to antibiotic therapy in malignant otitis externa--a case report.

作者信息

Paramsothy M, Khanijow V, Ong T O

机构信息

Department of Medicine, University Hospital, Kuala Lumpur, Malaysia.

出版信息

Singapore Med J. 1997 Aug;38(8):347-9.

PMID:9364890

Abstract

Malignant Otitis Externa (MOE) can cause considerable morbidity and mortality in affected individuals. The outlook is now much improved with the use of ciprofloxacin, but it is important to ascertain that the infection has been completely eradicated before stopping treatment, as undertreatment may lead to a recurrence which is usually more resistant than the initial infection. Gallium-67 Single Photon Emmision Computerised Tomography (SPECT) is a sensitive and cost effective tool in monitoring the disease activity of MOE, and should be used in the assessment of the response to antibiotic therapy.

摘要

恶性外耳道炎（MOE）可在受影响个体中导致相当高的发病率和死亡率。目前使用环丙沙星后预后已大为改善，但在停止治疗前确定感染已被彻底根除很重要，因为治疗不足可能导致复发，而复发通常比初始感染更具耐药性。镓-67单光子发射计算机断层扫描（SPECT）是监测MOE疾病活动的一种敏感且经济高效的工具，应用于评估对抗生素治疗的反应。