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沙眼衣原体感染在患有泌尿系统疾病女性中的作用

[The role of Chlamydia trachomatis infections in women with urinary tract diseases].

作者信息

Zdrodowska-Stefanow B, Darewicz B, Ostaszewska I, Puciło K

机构信息

Kliniki Dermatologii, Białymstoku.

出版信息

Pol Merkur Lekarski. 1997 Apr;2(10):270-2.

PMID:9377664
Abstract

The aim of our study was to determine the incidence of Chlamydia trachomatis (C. trachomatis) infections and its role in the etiopathogenesis of urinary tract infections in women. We studied 68 women, who where divided into two groups (I-with urethral syndrome, II-with other urologic diseases). With the use of direct diagnostic methods (immunofluorescence method, tissue culture) C. trachomatis infection was found in 25/68 (36.8%) women. In the group of women with urethral syndrome the percentage of positive results was higher in comparison to the second group, 53.8% and 26.2%, respectively. Specific antichlamydial antibodies of IgG class using direct immunoenzymatic method were found in 10/26 (38.5%) women with urethral syndrome. In the first group the infection was found more often in the urethra (urethra-85.7%, uterine cervix-50%) as in comparison to the second group. In the second group infection was found more often in the uterine cervix (urethra-45.5%, uterine cervix-72.7%). The incidence of C. trachomatis infection in women with urethral syndrome was in direct correlation with a larger number of polynuclear leukocytes in urine sediment (more than 3 in the viewing field). C. trachomatis infection was found in 76.5% of women with leukocyturia and 12.5% of women in which the number of leukocytes in urine sediment was less than 3 in the viewing field. The incidence of Ureaplasma urealyticum and Mycoplasma hominis infections between both study groups did not differ significantly. However, the incidence of yeast-like fungi infections in the group of women with other urologic diseases was double. The clinical sign most often found in women infected with C. trachomatis and with urethral syndrome was dysuria, which was present in all 14 women. In the group of women with other urologic diseases the clinical sign found most often was pollakisuria (72.7%).

摘要

我们研究的目的是确定沙眼衣原体(C. trachomatis)感染的发生率及其在女性尿路感染病因发病机制中的作用。我们研究了68名女性,她们被分为两组(I组——患有尿道综合征,II组——患有其他泌尿系统疾病)。通过直接诊断方法(免疫荧光法、组织培养),在25/68(36.8%)的女性中发现了沙眼衣原体感染。在患有尿道综合征的女性组中,阳性结果的百分比高于第二组,分别为53.8%和26.2%。使用直接免疫酶法在10/26(38.5%)患有尿道综合征的女性中发现了IgG类特异性抗衣原体抗体。与第二组相比,在第一组中感染更常发生于尿道(尿道——85.7%,子宫颈——50%)。在第二组中,感染更常发生于子宫颈(尿道——45.5%,子宫颈——72.7%)。患有尿道综合征的女性中沙眼衣原体感染的发生率与尿沉渣中多核白细胞数量较多直接相关(视野中超过3个)。在白细胞尿女性中,76.5%发现有沙眼衣原体感染,而尿沉渣中白细胞数量在视野中少于3个的女性中,这一比例为12.5%。两个研究组之间解脲脲原体和人型支原体感染的发生率没有显著差异。然而,患有其他泌尿系统疾病的女性组中酵母样真菌感染的发生率是两倍。感染沙眼衣原体且患有尿道综合征的女性中最常出现的临床症状是排尿困难,所有14名女性均有此症状。在患有其他泌尿系统疾病的女性组中最常发现的临床症状是尿频(72.7%)。

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