人类GLO基因位点的定位
Localization of the human GLO gene locus.
作者信息
Olaisen B, Gedde-Dahl T, Thorsby E
出版信息
Hum Genet. 1976 Jun 29;32(3):301-4. doi: 10.1007/BF00295820.
Data on the linkage relation between the GLO locus and the HLA, Bf, and PGM3 loci are presented. The family material includes 49 GLO/HLA-B (and/or Bf) segregating matings with 134 children informative on 199 parental meioses. Of phase-known meioses, 3 are recombinants and 75 nonrecombinants; linkage is therefore proven. From the total material a distance of 2.5 cM between GLO and HLA-B/Bf is calculated; and from the segregation in some informative family groups it is shown that GLO is situated between PGM3 and HLA-B/Bf.
本文给出了GLO基因座与HLA、Bf和PGM3基因座之间连锁关系的数据。家系资料包括49个GLO/HLA - B（和/或Bf）分离交配组合，其134名子女提供了199次亲代减数分裂的信息。在已知相位的减数分裂中，有3次重组和75次非重组；因此证明了连锁关系。根据全部资料计算出GLO与HLA - B/Bf之间的距离为2.5厘摩；并且从一些提供信息的家系组中的分离情况表明，GLO位于PGM3和HLA - B/Bf之间。
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