McGovern E, Moss H, Grewal G, Taylor A, Bjornsson S, Pell J
Stobhill Hospital, Glasgow.
Br J Gen Pract. 1997 Oct;47(423):635-7.
Use of folic acid supplements preconception, and during the first trimester, is associated with a reduced incidence of first and subsequent neural tube defects. The Department of Health guidelines recommend the use of folic acid supplements by all women planning a pregnancy.
To ascertain the proportion using folic acid supplements and the factors affecting their use.
Questionnaires were distributed postpartum to the 515 women who delivered normal babies in three maternity units in Glasgow over a four-week period.
Forms were completed by 487 (95%) women. Only 57% took supplements at some point during their pregnancy, and only 21% took them before conception. Failure to take supplements was significantly associated with unplanned pregnancy, younger age, and previous pregnancies. Lack of awareness of the potential benefits associated with folic acid use was the commonest reason cited by women for not taking supplements.
Increased health education through health care professionals and mass media campaigns can improve awareness and thereby increase the use of supplements in planned pregnancies. However, 42% of women in our study had unplanned pregnancies. Intake of folic acid supplements in this group can only be increased by improvements in dietary intake within the population as a whole, and by fortification of commonly ingested foods.
孕前及孕早期补充叶酸与降低首次及后续神经管缺陷的发生率相关。卫生部指南建议所有计划怀孕的女性补充叶酸。
确定补充叶酸的女性比例及其影响因素。
在四周时间内,向格拉斯哥三个产科病房分娩正常婴儿的515名女性发放产后调查问卷。
487名(95%)女性填写了问卷。只有57%的女性在孕期的某个阶段服用了补充剂,只有21%的女性在孕前服用。未服用补充剂与意外怀孕、年龄较小和既往怀孕显著相关。女性未服用补充剂最常见的原因是缺乏对叶酸使用潜在益处的认识。
通过医护人员和大众媒体宣传活动加强健康教育可以提高认识,从而增加计划怀孕女性补充剂的使用。然而,我们研究中的42%女性意外怀孕。只有通过提高整个人口的饮食摄入量以及强化常见食用食品,才能增加这一群体的叶酸补充剂摄入量。