[The effect of the delta sleep-inducing peptide on NMDA-induced seizure activity in rats].
作者信息
Shandra A A, Godlevskiĭ L S, Brusentsov A I, Karliuga V A
机构信息
State Medical University, Odessa, Ukraine.
出版信息
Ross Fiziol Zh Im I M Sechenova. 1997 Sep;83(9):32-6.
PMID:9487065
Abstract
The ED100 of the NMDA inducing clonic seizures (0.53 mcg) or tonic extension of forelimbs (5.02 mcg) increased their efficiency 2.3-fold and 4.46-fold, resp., due to the delta-sleep-inducing peptide administration in rats. The data obtained suggests a neuroprotective effect of the peptide on agonists of excitatory amino acid receptors action.
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