Skowronek J, Roszak A
Wielkopolskiego Centrum Onkologii.
Ginekol Pol. 1997 Aug;68(8):390-3.
Primary vaginal malignant melanoma is an uncommon disease with poor prognosis. As compared with malignant melanoma of the skin, vaginal melanoma infiltrates early deep into tissues and in the abundant lymph and blood vascularisation. Epidemiology, clinical and histopathological data and treatment methods of primary and metastatic vaginal melanoma are discussed. A case of 53 years old women with malignant melanoma of the skin with metastasis to vagina treated in Wielkopolska Center of Oncology is presented. According to the literature aggressive surgical therapy can improve greatly the outlook for patients with vaginal melanoma.
原发性阴道恶性黑色素瘤是一种预后较差的罕见疾病。与皮肤恶性黑色素瘤相比,阴道黑色素瘤早期即深入浸润组织,且有丰富的淋巴和血管分布。本文讨论了原发性和转移性阴道黑色素瘤的流行病学、临床及组织病理学数据以及治疗方法。文中介绍了一位53岁女性患者的病例,该患者患有皮肤恶性黑色素瘤并已转移至阴道,在大波兰肿瘤中心接受了治疗。根据文献报道,积极的手术治疗可显著改善阴道黑色素瘤患者的预后。