Quantitative structure-activity relationship study of some 7-substituted theophyllines.
作者信息
Türker L, Akgün H, Balkan A
机构信息
Middle East Technical University, Department of Chemistry, Ankara, Turkey.
出版信息
Arzneimittelforschung. 1998 Jan;48(1):39-42.
PMID:9522029
Abstract
Some novel 7-substituted theophylline derivatives have been investigated for quantitative structure-activity relationship (QSAR). For this purpose, their bronchodilatory activities (in vitro), which were examined by the inhibition of acetylcholine induced contraction in tracheae isolated from guinea pigs, have been correlated with various quantum chemical and physicochemical parameters.
摘要
Zotero 插件