几种正构烷烃对磷脂六方相影响的比较研究
Comparative study of the effects of several n-alkanes on phospholipid hexagonal phases.
作者信息
Chen Z, Rand R P
机构信息
Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada.
出版信息
Biophys J. 1998 Feb;74(2 Pt 1):944-52. doi: 10.1016/S0006-3495(98)74017-2.
Abstract
The effects of a series of normal alkanes (decane, dodecane, tetradecane, hexadecane, and octadecane) on the hexagonal H(II) structures containing dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC) were studied using x-ray diffraction and osmotic stress. The alkanes affect structural dimensions and the monolayer intrinsic curvature and bending modulus. The alkane effects are chain-length dependent and are attributed to their different distribution within the H(II) structure. The data suggest that short-chain alkanes are more uniformly distributed within the H(II) hydrocarbon regions and change the curvature and bending modulus of the monolayer, whereas longer-chain alkanes appear confined more to the interstitial region and do not change the curvature and bending modulus.
摘要
利用X射线衍射和渗透应力研究了一系列正构烷烃（癸烷、十二烷、十四烷、十六烷和十八烷）对含有二油酰磷脂酰乙醇胺（DOPE）和二油酰磷脂酰胆碱（DOPC）的六方H(II)结构的影响。这些烷烃会影响结构尺寸以及单层的固有曲率和弯曲模量。烷烃的影响取决于链长，这归因于它们在H(II)结构内的不同分布。数据表明，短链烷烃在H(II)碳氢区域内分布更均匀，会改变单层的曲率和弯曲模量，而长链烷烃似乎更多地局限于间隙区域，不会改变曲率和弯曲模量。
相似文献
1
Comparative study of the effects of several n-alkanes on phospholipid hexagonal phases.几种正构烷烃对磷脂六方相影响的比较研究
Biophys J. 1998 Feb;74(2 Pt 1):944-52. doi: 10.1016/S0006-3495(98)74017-2.
2
The influence of cholesterol on phospholipid membrane curvature and bending elasticity.胆固醇对磷脂膜曲率和弯曲弹性的影响。
Biophys J. 1997 Jul;73(1):267-76. doi: 10.1016/S0006-3495(97)78067-6.
3
Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress.双溶剂胁迫下磷脂的膜曲率、脂质分离及结构转变
Biochemistry. 1990 Jan 9;29(1):76-87. doi: 10.1021/bi00453a010.
4
New phases of phospholipids and implications to the membrane fusion problem.磷脂的新相及其对膜融合问题的影响。
Biochemistry. 2003 Jun 10;42(22):6631-5. doi: 10.1021/bi0344836.
5
The influence of lysolipids on the spontaneous curvature and bending elasticity of phospholipid membranes.溶血磷脂对磷脂膜自发曲率和弯曲弹性的影响。
Biophys J. 2001 Jul;81(1):243-54. doi: 10.1016/S0006-3495(01)75695-0.
6
Distribution of decane within the unit cell of the inverted hexagonal (HII) phase of lipid-water-decane systems determined by neutron diffraction.通过中子衍射确定脂质 - 水 - 癸烷体系反六角（HII）相晶胞内癸烷的分布。
Biochemistry. 1992 Feb 11;31(5):1356-63. doi: 10.1021/bi00120a010.
7
Role of the position of unsaturation on the phase behavior and intrinsic curvature of phosphatidylethanolamines.不饱和键位置对磷脂酰乙醇胺相行为和固有曲率的作用。
Biophys J. 1996 Oct;71(4):1806-10. doi: 10.1016/S0006-3495(96)79381-5.
8
Phase behavior of the DOPE + DOPC + alkanol system.
Soft Matter. 2014 Aug 21;10(31):5842-8. doi: 10.1039/c4sm00530a. Epub 2014 Jun 30.
9
Bending, hydration and interstitial energies quantitatively account for the hexagonal-lamellar-hexagonal reentrant phase transition in dioleoylphosphatidylethanolamine.弯曲能、水合能和界面能定量地解释了二油酰磷脂酰乙醇胺中的六方-层状-六方折返相变。
Biophys J. 1994 Oct;67(4):1603-11. doi: 10.1016/S0006-3495(94)80633-2.
10
Curvature and bending constants for phosphatidylserine-containing membranes.含磷脂酰丝氨酸膜的曲率和弯曲常数。
Biophys J. 2003 Sep;85(3):1667-74. doi: 10.1016/s0006-3495(03)74596-2.
引用本文的文献
1
Effects of spontaneous curvature on interfacial adsorption and collapse of phospholipid monolayers.自发曲率对磷脂单分子层界面吸附和塌陷的影响。
Am J Physiol Lung Cell Mol Physiol. 2024 Dec 1;327(6):L876-L882. doi: 10.1152/ajplung.00193.2024. Epub 2024 Oct 22.
2
Exploring the Properties of Curved Lipid Membranes: Comparative Analysis of Atomistic and Coarse-Grained Force Fields.探究弯曲脂质膜的性质：原子力场和粗粒化力场的比较分析。
J Phys Chem B. 2024 Jul 25;128(29):7160-7171. doi: 10.1021/acs.jpcb.4c02310. Epub 2024 Jul 11.
3
Softening in Two-Component Lipid Mixtures by Spontaneous Curvature Variance.双组份脂质混合物的自发曲率变化致软化。
J Phys Chem B. 2024 Jul 4;128(26):6317-6326. doi: 10.1021/acs.jpcb.3c08117. Epub 2024 Jun 18.
4
Softening in two-component lipid mixtures by spontaneous curvature variance.通过自发曲率变化实现双组分脂质混合物的软化
bioRxiv. 2023 Dec 13:2023.12.12.571323. doi: 10.1101/2023.12.12.571323.
5
Curvature Energetics Determined by Alchemical Simulation on Four Topologically Distinct Lipid Phases.通过对四种拓扑结构不同的脂质相的化学模拟确定曲率能量。
J Phys Chem B. 2021 Feb 25;125(7):1815-1824. doi: 10.1021/acs.jpcb.0c09458. Epub 2021 Feb 11.
6
Computer simulations of protein-membrane systems.蛋白质-膜系统的计算机模拟。
Prog Mol Biol Transl Sci. 2020;170:273-403. doi: 10.1016/bs.pmbts.2020.01.001. Epub 2020 Feb 26.
7
Global small-angle scattering data analysis of inverted hexagonal phases.反六角相的全球小角散射数据分析
J Appl Crystallogr. 2019 Mar 28;52(Pt 2):403-414. doi: 10.1107/S1600576719002760. eCollection 2019 Apr 1.
8
BUMPy: A Model-Independent Tool for Constructing Lipid Bilayers of Varying Curvature and Composition.BUMPy：一种用于构建具有变化曲率和组成的脂质双层的模型独立工具。
J Chem Theory Comput. 2018 Dec 11;14(12):6642-6652. doi: 10.1021/acs.jctc.8b00765. Epub 2018 Nov 29.
9
Hydrophobic surfactant proteins strongly induce negative curvature.疏水表面活性蛋白强烈诱导负曲率。
Biophys J. 2015 Jul 7;109(1):95-105. doi: 10.1016/j.bpj.2015.05.030.
10
The location of coenzyme Q10 in phospholipid membranes made of POPE: a small-angle synchrotron X-ray diffraction study.辅酶Q10在由1-棕榈酰-2-油酰基磷脂酰乙醇胺制成的磷脂膜中的位置：小角同步加速器X射线衍射研究
Eur Biophys J. 2015 Jul;44(5):373-81. doi: 10.1007/s00249-015-1031-z. Epub 2015 Jun 4.
本文引用的文献
1
The structure of the liquid-crystalline phasis of lipid-water systems.脂质 - 水体系液晶相的结构。
J Cell Biol. 1962 Feb;12(2):207-19. doi: 10.1083/jcb.12.2.207.
2
The influence of cholesterol on phospholipid membrane curvature and bending elasticity.胆固醇对磷脂膜曲率和弯曲弹性的影响。
Biophys J. 1997 Jul;73(1):267-76. doi: 10.1016/S0006-3495(97)78067-6.
3
Lipid bilayer electrostatic energy, curvature stress, and assembly of gramicidin channels.脂质双分子层静电能、曲率应力与短杆菌肽通道组装
Biochemistry. 1997 May 13;36(19):5695-701. doi: 10.1021/bi9619841.
4
Measured effects of diacylglycerol on structural and elastic properties of phospholipid membranes.二酰基甘油对磷脂膜结构和弹性性质的测量效应。
Biophys J. 1996 Nov;71(5):2623-32. doi: 10.1016/S0006-3495(96)79454-7.
5
Correlation between lipid plane curvature and lipid chain order.脂质平面曲率与脂质链有序性之间的相关性。
Biophys J. 1996 Jun;70(6):2747-57. doi: 10.1016/S0006-3495(96)79844-2.
6
Role of lipid polymorphism in pulmonary surfactant.脂质多态性在肺表面活性物质中的作用。
Science. 1996 Jul 19;273(5273):330-2. doi: 10.1126/science.273.5273.330.
7
Influence of local and neutral anaesthetics on the polymorphic phase preferences of egg yolk phosphatidylethanolamine.
Biochim Biophys Acta. 1981 Oct 2;647(2):285-92. doi: 10.1016/0005-2736(81)90256-x.
8
Elastic properties of lipid bilayers: theory and possible experiments.脂质双层膜的弹性特性：理论与可能的实验
Z Naturforsch C. 1973 Nov-Dec;28(11):693-703. doi: 10.1515/znc-1973-11-1209.
9
Diacylglycerols, lysolecithin, or hydrocarbons markedly alter the bilayer to hexagonal phase transition temperature of phosphatidylethanolamines.二酰基甘油、溶血卵磷脂或碳氢化合物会显著改变磷脂酰乙醇胺从双层相到六方相的转变温度。
Biochemistry. 1985 Dec 3;24(25):7092-5. doi: 10.1021/bi00346a011.
10
Intrinsic curvature hypothesis for biomembrane lipid composition: a role for nonbilayer lipids.生物膜脂质组成的内在曲率假说：非双层脂质的作用。
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3665-9. doi: 10.1073/pnas.82.11.3665.
Zotero 插件