用人类绒毛膜促性腺激素治疗合成代谢类固醇诱导的性腺功能减退。
Anabolic steroid induced hypogonadism treated with human chorionic gonadotropin.
作者信息
Gill G V
机构信息
Endocrine Unit, Walton Hospital, Liverpool, UK.
出版信息
Postgrad Med J. 1998 Jan;74(867):45-6. doi: 10.1136/pgmj.74.867.45.
Abstract
A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully treated with weekly injections of human chorionic gonadotropin for three months. Testicular function remained normal thereafter on no treatment. The use of human chorionic gonadotropin should be considered in prolonged hypogonadotrophic hypogonadism due to anabolic steroid abuse.
摘要
本文介绍了一例年轻的竞技健美运动员，他滥用合成代谢类固醇药物，导致严重的症状性低促性腺激素性性腺功能减退。在使用处方睾酮（长效睾酮）的帮助下，他停止服用合成代谢药物，后来也停用了长效睾酮。性腺功能减退复发，但通过每周注射人绒毛膜促性腺激素进行三个月的治疗后成功治愈。此后未经治疗，睾丸功能仍保持正常。对于因滥用合成代谢类固醇导致的长期低促性腺激素性性腺功能减退，应考虑使用人绒毛膜促性腺激素。
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本文引用的文献
1
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2
Neuropsychiatric effects of anabolic steroids in male normal volunteers.合成代谢类固醇对男性正常志愿者的神经精神影响。
JAMA. 1993 Jun 2;269(21):2760-4.
3
Anabolic steroids in athletics: how well do they work and how dangerous are they?体育界中的合成代谢类固醇：它们的效果如何，危险性又有多大？
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4
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J Steroid Biochem. 1986 Jul;25(1):109-12. doi: 10.1016/0022-4731(86)90288-8.
5
Drug abuse in body builders in the West of Scotland.苏格兰西部健美运动员中的药物滥用情况。
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