一名获得性免疫缺陷综合征患者出现皮肤损害的播散性组织胞浆菌病。
Disseminated histoplasmosis presenting with cutaneous lesions in a patient with acquired immunodeficiency syndrome.
作者信息
Angius A G, Viviani M A, Muratori S, Cusini M, Brignolo L, Alessi E
机构信息
Institute of Dermatological Sciences of the University of Milan, IRCCS Ospedale Maggiore of Milan, Italy.
出版信息
J Eur Acad Dermatol Venereol. 1998 Mar;10(2):182-5.
OBJECTIVE
Presentation of a case of disseminated histoplasmosis, observed in a non-endemic area, in which cutaneous lesions and fever were the dominant clinical signs of the infection.
CASE
A 54-year-old homosexual man with acquired immunodeficiency syndrome (AIDS) related Kaposi's sarcoma presented with cutaneous lesions and fever due to disseminated histoplasmosis. The patient was successfully treated with itraconazole 200 mg/day. He died after 8 months from AIDS dementia complex: disseminated histoplasmosis relapse was not observed.
CONCLUSION
The case shows that infection with Histoplasma capsulatum must be considered by dermatologists in HIV/AIDS patients, even in non-endemic areas.
目的
介绍一例在非流行地区观察到的播散性组织胞浆菌病病例，其中皮肤病变和发热是该感染的主要临床症状。
病例
一名54岁患有获得性免疫缺陷综合征（AIDS）相关卡波西肉瘤的同性恋男子，因播散性组织胞浆菌病出现皮肤病变和发热。患者接受每日200毫克伊曲康唑治疗后痊愈。8个月后，他死于艾滋病痴呆综合征：未观察到播散性组织胞浆菌病复发。
结论
该病例表明，即使在非流行地区，皮肤科医生也必须考虑HIV/AIDS患者感染荚膜组织胞浆菌的可能性。
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