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老年女性肱骨远端骨质疏松性骨折的长期趋势。

Secular trends in the osteoporotic fractures of the distal humerus in elderly women.

作者信息

Palvanen M, Kannus P, Niemi S, Parkkari J

机构信息

Accident & Trauma Research Center, UKK Institute for Health Promotion Research, Tampere, Finland.

出版信息

Eur J Epidemiol. 1998 Feb;14(2):159-64. doi: 10.1023/a:1007496318884.

Abstract

Osteoporosis, with its sequelae of fracture, is a major, continuously increasing threat to the health of the elderly, and therefore reliable epidemiological information is needed for assessment of the fracture development in the future and for effective fracture prevention. However, very little population-based information is available concerning the nationwide numbers, incidences and especially secular trends of osteoporotic fractures other than those occurring at the hip. We determined the current trends in the number and incidence of osteoporotic fractures of the distal humerus in Finnish women in 1970-1995 by collecting from the National Hospital Discharge Register all female patients aged 60 years or more who were admitted to our hospitals in 1970-1972, 1974-1975, 1978-1980, 1983-1985 and 1988-1995 for primary treatment of first osteoporotic fracture of the distal humerus. The fracture was defined as osteoporotic if it occurred on individuals aged 60 years or more as a consequence of a moderate or minimal trauma only (a fall from standing height or less). We also predicted the fracture development till the year 2030 by a regression model, a model that took into account the predicted changes in the fracture incidences and population at risk. The number and incidence (per 100,000 women) of osteoporotic fractures of the distal humerus in Finnish women aged 60 years or more increased from 42 (number) and 11 (incidence) in 1970 to 175 and 30 in 1995. The age-adjusted incidence of osteoporotic fractures of the distal humerus also increased, from 12/100,000 women in 1970 to 28/100,000 women in 1995. If this trend continues, the number of these fractures in Finnish women will be almost three-fold in the year 2030 compared with that in 1995. We conclude that the number of osteoporotic fractures of the distal humerus in elderly Finnish women is increasing more rapidly than can be accounted for by the demographic changes alone and therefore effective preventive measures are imperative to keep this problem in control.

摘要

骨质疏松症及其骨折后遗症是对老年人健康的一个重大且持续增加的威胁,因此需要可靠的流行病学信息来评估未来骨折的发展情况并有效预防骨折。然而,除了髋部骨折外,关于全国范围内骨质疏松性骨折的数量、发病率,尤其是长期趋势,基于人群的信息非常少。我们通过从国家医院出院登记处收集1970 - 1972年、1974 - 1975年、1978 - 1980年、1983 - 1985年和1988 - 1995年因首次肱骨远端骨质疏松性骨折而入住我们医院的所有60岁及以上女性患者,确定了1970 - 1995年芬兰女性肱骨远端骨质疏松性骨折的数量和发病率的当前趋势。如果骨折仅因中度或轻度创伤(从站立高度或更低处跌倒)发生在60岁及以上的个体身上,则定义为骨质疏松性骨折。我们还通过回归模型预测了到2030年的骨折发展情况,该模型考虑了骨折发病率和高危人群的预测变化。60岁及以上芬兰女性肱骨远端骨质疏松性骨折的数量(例数)和发病率(每10万名女性)从1970年的42例(数量)和11例(发病率)增加到1995年的175例和30例。肱骨远端骨质疏松性骨折的年龄调整发病率也有所增加,从1970年的每10万名女性12例增加到1995年的每10万名女性28例。如果这种趋势持续下去,到2030年芬兰女性这些骨折的数量将比1995年增加近两倍。我们得出结论,芬兰老年女性肱骨远端骨质疏松性骨折的数量增长速度比仅由人口结构变化所能解释的速度要快,因此必须采取有效的预防措施来控制这一问题。

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