Testa G, Goldstein R M, Toughanipour A, Abbasoglu O, Jeyarajah R, Levy M F, Husberg B S, Gonwa T A, Klintmalm G B
Baylor University Medical Center, Transplant Department, Dallas, Texas 75246, USA.
Ann Surg. 1998 Apr;227(4):590-9. doi: 10.1097/00000658-199804000-00023.
The first purpose of this study is to identify the types and incidences of surgical procedures in patients who have previously undergone liver transplantation, with particular focus on the complication rates and the lengths of hospital stay. The second purpose is to present the management guidelines for patients with liver transplants at the preoperative, intraoperative, and postoperative stages of surgical procedure.
The surgical literature on this issue is scant, and with the growing liver transplant patient population it is not unlikey for any surgery specialist to have to operate on a patient who has undergone liver transplantation.
A sample of 409 patients with available hospital records, with a minimum of a 2-year follow-up, and with telephone access for interviews was chosen. Type of surgery, time from the liver transplant, hospital stay, immunosuppressive regimen, and complications were recorded.
A large proportion of patients (24.2%) underwent some type of surgical procedure 2 to 10 years after liver transplantation. The authors demonstrate that most of the elective procedures can be safely carried out without an increased incidence of complication and without longer hospital stay than the general population. Conversely, emergent procedures are plagued by a greater incidence of complications that not only affect the function of the liver graft but may risk the life of the patient.
本研究的首要目的是确定既往接受过肝移植的患者所接受的外科手术类型及发生率,尤其关注并发症发生率和住院时长。第二个目的是提出肝移植患者在手术前、手术中和手术后阶段的管理指南。
关于这个问题的外科文献很少,并且随着肝移植患者群体的不断增加,任何外科专家都有可能不得不为接受过肝移植的患者进行手术。
选取了409例有可用医院记录、至少随访2年且可通过电话进行访谈的患者。记录手术类型、肝移植后的时间、住院时间、免疫抑制方案及并发症情况。
很大一部分患者(24.2%)在肝移植后2至10年接受了某种类型的外科手术。作者表明,大多数择期手术可以安全进行,并发症发生率不会增加,住院时间也不会比普通人群更长。相反,急诊手术并发症发生率更高,不仅会影响肝移植的功能,还可能危及患者生命。