Chamberlain M C
University of California, San Diego, La Jolla, CA, USA.
Neurology. 1998 Apr;50(4):1173-5. doi: 10.1212/wnl.50.4.1173.
Eighteen patients (age range, 28 to 62 years; median, 58) with carcinomatous meningitis defined clinically (100%) and neuroradiographically (39%) with negative CSF cytology were evaluated with CSF biochemical markers. In only four patients (22%), CSF biochemical markers corroborated a diagnosis of carcinomatous meningitis.
18例临床诊断为癌性脑膜炎(100%)且神经影像学诊断为癌性脑膜炎(39%)但脑脊液细胞学检查阴性的患者(年龄范围28至62岁;中位数58岁)接受了脑脊液生化标志物评估。仅4例患者(22%)的脑脊液生化标志物证实了癌性脑膜炎的诊断。