Svane-Knudsen V, Jørgensen K E, Hansen O, Lindgren A, Marker P
Department of Otorhinolaryngology, University Hospital, Odense, Denmark.
Rhinology. 1998 Mar;36(1):12-4.
A total of 115 patients with sinonasal cancer was assessed during the period 1978-1995. Ninety-one patients received treatment with curative intent. A combination of irradiation and operation was used. The 5-year crude survival for patients, who were treated with curative intent, was 41%; the disease-specific survival throughout the period was 48%. Primary irradiation followed by maxillectomy was widely used in the first half of the period. Treatment in the last part was changed to primary lateral rhinotomy with post-operative irradiation whenever possible. Twelve maxillectomies were performed during the first half of the period, and during the last part, only two. Disease-specific survival was equal in the first and the second halves of the period.
1978年至1995年期间,共评估了115例鼻窦癌患者。91例患者接受了根治性治疗,采用了放疗与手术相结合的方法。接受根治性治疗患者的5年粗生存率为41%;整个时期的疾病特异性生存率为48%。在该时期的前半段,广泛采用先放疗后行上颌骨切除术的治疗方法。在后半段,治疗方法改为尽可能先进行外侧鼻切开术,术后再放疗。该时期前半段进行了12例上颌骨切除术,后半段仅进行了2例。该时期前半段和后半段的疾病特异性生存率相同。