晚期卵巢小细胞癌中子宫和卵巢的保留
Uterine and ovarian conservation in advanced small cell carcinoma of the ovary.
作者信息
Powell J L, McAfee R D, McCoy R C, Shiro B S
机构信息
Department of Obstetrics and Gynecology, Coastal Area Health Education Center, New Hanover Regional Medical Center, Wilmington, North Carolina 28402-9025, USA.
出版信息
Obstet Gynecol. 1998 May;91(5 Pt 2):846-8. doi: 10.1016/s0029-7844(98)00025-8.
BACKGROUND
The decision to recommend removal or conservation of a normal ovary and uterus in a young woman with advanced ovarian cancer is difficult and controversial.
CASE
A 21-year-old patient with a large-cell variant of small-cell carcinoma of the ovary stage IIIc underwent optimal debulking surgery with preservation of the normal appearing uterus and opposite adnexa followed by aggressive multi-agent chemotherapy. She is menstruating normally and is free of disease, more than 2 years since completion of chemotherapy.
CONCLUSION
In selected cases, conservation of the uninvolved ovary and uterus in patients with advanced-stage, small-cell carcinoma of the ovary may not compromise survival.
背景
对于患有晚期卵巢癌的年轻女性，决定是否建议切除或保留正常卵巢和子宫是困难且存在争议的。
病例
一名21岁患有卵巢小细胞癌大细胞变异型Ⅲc期的患者接受了最佳肿瘤细胞减灭术，术中保留了外观正常的子宫和对侧附件，随后进行了积极的多药联合化疗。化疗结束已逾2年，她月经正常且无疾病迹象。
结论
在某些特定病例中，对于晚期卵巢小细胞癌患者保留未受累的卵巢和子宫可能不会影响生存率。
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