从墨西哥尤卡坦半岛坎佩切州局部皮肤利什曼病患者中分离出的利什曼原虫的同工酶特征分析。
Isoenzyme characterization of Leishmania isolated from human cases with localized cutaneous leishmaniasis from the State of Campeche, Yucatan Peninsula, Mexico.
作者信息
Canto-Lara S B, Cardenas-Maruffo M F, Vargas-Gonzalez A, Andrade-Narvaez F
机构信息
Departamento de Immunologia, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autonoma de Yucatan, Merida, Mexico.
出版信息
Am J Trop Med Hyg. 1998 Apr;58(4):444-7. doi: 10.4269/ajtmh.1998.58.444.
Seventy-five isolates from the State of Campeche, Mexico, an area endemic for localized cutaneous leishmaniasis (LCL), were characterized by isoenzyme markers (glucose phosphate isomerase, mannose phospate isomerase, nucleoside hydrolase, phosphoglucomutase, 6-phosphogluconate dehydrogenase, and glucose-6-phosphate dehydrogenase). Seventy (93.3%) were identified as Leishmania (Leishmania) mexicana and 5 (6.7%) as L. (Viannia) braziliensis. This is the first report of authochthonus human LCL caused by L. (V.) braziliensis in the State of Campeche, Yucatan Peninsula, Mexico.
从墨西哥坎佩切州（一个局部皮肤利什曼病的流行地区）分离出75株菌株，通过同工酶标记物（葡萄糖磷酸异构酶、甘露糖磷酸异构酶、核苷水解酶、磷酸葡萄糖变位酶、6-磷酸葡萄糖酸脱氢酶和葡萄糖-6-磷酸脱氢酶）进行特征鉴定。其中70株（93.3%）被鉴定为墨西哥利什曼原虫（利什曼原虫属），5株（6.7%）为巴西利什曼原虫（维扬尼利什曼原虫亚属）。这是墨西哥尤卡坦半岛坎佩切州由巴西利什曼原虫（维扬尼利什曼原虫亚属）引起的本土人类局部皮肤利什曼病的首次报告。
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