Tsuji Y, Yamashita C, Wakiyama H, Toyoda Y, Yoshida M, Sugimoto T, Ataka K, Ishii N, Shida T, Okada M
Department of Surgery, Kobe University School of Medicine, Japan.
J Vasc Surg. 1998 Apr;27(4):740-4. doi: 10.1016/s0741-5214(98)70241-1.
From 1984 to 1996, four patients with transvenous intracardiac tumor extension underwent operations in the Kobe University Hospital. The primary tumors of two were intravenous leiomyomatoses originating from the uterus; a third patient had invasive thymoma, and the fourth patient had clear cell sarcoma of the kidney. In 1985, one patient had a curative, staged resection. One-stage operations were carried out in three patients, and all intracardiac tumors were successfully resected en bloc with the primary tumors under conditions of electrical ventricular fibrillation and mild hypothermia. Combined venous reconstructions were necessary for en bloc resection in three cases. Two patients with malignancy received postoperative chemoradiotherapy, and all four patients were discharged uneventfully from our hospital. We consider radical resection with curative intent only for patients with tumors extending into the heart. In these cases, a one-stage operation is preferable, and electrical ventricular fibrillation with mild hypothermia is a recommended method of circulatory assist because of its simplicity.
1984年至1996年期间,4例经静脉发生心内肿瘤扩展的患者在神户大学医院接受了手术。其中2例的原发肿瘤为起源于子宫的静脉内平滑肌瘤病;第3例患者患有侵袭性胸腺瘤,第4例患者患有肾透明细胞肉瘤。1985年,1例患者接受了根治性分期切除。3例患者接受了一期手术,在心室颤动和轻度低温的条件下,所有心内肿瘤均与原发肿瘤一起成功整块切除。3例患者整块切除需要进行联合静脉重建。2例恶性肿瘤患者接受了术后放化疗,所有4例患者均顺利出院。我们认为仅对肿瘤扩展至心脏的患者进行根治性切除。在这些病例中,一期手术更为可取,由于其操作简单,心室颤动和轻度低温是推荐的循环辅助方法。