Effect of cisapride on myoelectrical activity of the gastrointestinal tract in the conscious miniature pig.
作者信息
Wechsung E, Houvenaghel A
机构信息
Laboratory of Veterinary Physiology, University Centre of Antwerp, Belgium.
出版信息
Zentralbl Veterinarmed A. 1998 Mar;45(2):63-8. doi: 10.1111/j.1439-0442.1998.tb00801.x.
Abstract
In conscious miniature pigs with electrodes implanted in the wall of the antrum pylori, duodenum, jejunum, ileum and caecum, the influence of intravenous injection of cisapride, 0.5 and 1 mg/kg, on gastrointestinal myoelectrical activity, was examined. Cisapride, 1 mg/kg, induced a delayed and sustained increase in antral myoelectrical activity. The studied intestinal segments were rather insensitive to the stimulating effect of the benzamide, since only the jejunum and the caecum revealed an increase in myoelectrical activity with the higher dose studied.
摘要
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