由甲氧苄啶本身及复方新诺明引起的全身性红斑性皮肤疹。

Generalized erythematous skin eruptions due to trimethoprim itself and co-trimoxazole.

作者信息

Hattori N, Hino H

机构信息

Department of Dermatology, Kanto Central Hospital, Tokyo, Japan.

出版信息

J Dermatol. 1998 Apr;25(4):269-71. doi: 10.1111/j.1346-8138.1998.tb02395.x.

DOI:10.1111/j.1346-8138.1998.tb02395.x

PMID:9609988

Abstract

A 20-year-old Japanese woman (Case 1) and a 70-year-old Japanese man (Case 2) consulted us with slight fever and disseminated erythematous papules. Examinations revealed that the first case was a skin eruption due to trimethoprim itself and the second was due to both trimethoprim and sulphamethoxazole. To our knowledge, our Case 1 is the first reported case with an erythematous papular type skin eruption caused by trimethoprim itself, and our Case 2 is the first case of a skin eruption in reaction to both trimethoprim and sulphamethoxazole.

摘要

一名20岁的日本女性（病例1）和一名70岁的日本男性（病例2）因低热和散在性红斑丘疹前来就诊。检查发现，第一例是由甲氧苄啶本身引起的皮疹，第二例是由甲氧苄啶和磺胺甲恶唑共同引起的。据我们所知，我们的病例1是首例报道的由甲氧苄啶本身引起的红斑丘疹型皮疹病例，我们的病例2是首例对甲氧苄啶和磺胺甲恶唑均产生反应的皮疹病例。