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糖皮质激素注射到慢性肌痛患者咬肌浅层的短期效果:纤维肌痛与局限性肌痛的比较

Short-term effect of glucocorticoid injection into the superficial masseter muscle of patients with chronic myalgia: a comparison between fibromyalgia and localized myalgia.

作者信息

Ernberg M, Hedenberg-Magnusson B, Alstergren P, Kopp S

机构信息

Department of Clinical Oral Physiology, Faculty of Dentistry, Karolinska Institute, Huddinge, Sweden.

出版信息

J Orofac Pain. 1997 Summer;11(3):249-57.

PMID:9610315
Abstract

The aim of this study was to investigate whether the treatment effect of intramuscular glucocorticoid injection differs between patients with fibromyalgia and those with localized myalgia of the masseter muscle concerning pain, tenderness to digital palpation, pressure pain threshold, pressure pain tolerance level, maximum voluntary occlusal force, or intramuscular temperature. Twenty-five patients with fibromyalgia and 25 patients with localized myalgia of the masseter muscle were first asked to assess their pain on a visual analogue scale; afterward, a routine clinical examination, including tenderness to digital palpation, was performed. For each patient, the pressure pain threshold, pressure pain tolerance level, and maximum voluntary occlusal force, as well as the intramuscular temperature, were recorded. Finally each patient received an injection of glucocorticoid. The examination and glucocorticoid treatment were repeated after approximately 2 weeks, and a follow-up was performed after another 5 weeks. In the fibromyalgia group, there was a reduced tenderness to digital palpation in response to the treatment. The localized myalgia group responded with a general improvement of symptoms as well as a significant reduction of pain intensity and tenderness to digital palpation. The results of this study indicate that patients with fibromyalgia and localized myalgia in many respects show a similar response to local glucocorticoid treatment.

摘要

本研究的目的是调查在疼痛、指触压痛、压痛阈值、压痛耐受水平、最大自主咬合力或肌肉内温度方面,肌内注射糖皮质激素对纤维肌痛患者和咬肌局部肌痛患者的治疗效果是否存在差异。首先要求25例纤维肌痛患者和25例咬肌局部肌痛患者采用视觉模拟评分法评估其疼痛程度;随后,进行包括指触压痛在内的常规临床检查。记录每位患者的压痛阈值、压痛耐受水平、最大自主咬合力以及肌肉内温度。最后,每位患者接受一次糖皮质激素注射。约2周后重复进行检查和糖皮质激素治疗,再过5周进行随访。在纤维肌痛组,治疗后指触压痛减轻。局部肌痛组症状总体改善,疼痛强度和指触压痛显著减轻。本研究结果表明,纤维肌痛患者和局部肌痛患者在许多方面对局部糖皮质激素治疗的反应相似。

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