Ramsey P S, Van Winter J T, Gaffey T A, Ramin K D
Department of Obstetrics/Gynecology, Mayo Medical Center, Rochester, Minnesota 55905, USA.
J Reprod Med. 1998 May;43(5):456-8.
Eclampsia is a rare and serious complication of pregnancy. The occurrence of preeclampsia prior to the 20th week of gestation has been associated with concurrent hydatidiform molar pregnancy. We present a case of eclampsia complicating a partial molar pregnancy associated with a viable fetus.
A 22-year-old white woman, gravida 1, para 0, at 14 weeks' gestation, presented with an excruciating headache associated with hypertension, proteinuria and a viable intrauterine fetus with gastroschisis. Subsequently the patient had a generalized tonic-clonic seizure which resolved with magnesium sulfate therapy. Markedly elevated quantitative human chorionic gonadotropin and a moderately thickened placenta were the sole clinical features suggestive of a molar gestation. Dilation and evacuation was performed revealing unremarkable products of conception. Pathologic and cytogenetic analyses revealed a triploid fetus (69,XXX) consistent with partial molar pregnancy.
Development of preeclampsia/eclampsia prior to 20 weeks of gestation should prompt a clinical evaluation to exclude the possibility of an underlying hydatidiform molar pregnancy.
子痫是一种罕见且严重的妊娠并发症。妊娠20周前发生的先兆子痫与同期葡萄胎妊娠有关。我们报告一例子痫并发部分性葡萄胎妊娠且伴有存活胎儿的病例。
一名22岁白人女性，孕1产0，妊娠14周，因剧烈头痛伴高血压、蛋白尿就诊，子宫内有一存活胎儿并伴有腹裂。随后患者发生全身强直阵挛性癫痫发作，经硫酸镁治疗后缓解。定量人绒毛膜促性腺激素显著升高和胎盘中度增厚是提示葡萄胎妊娠的唯一临床特征。行扩张刮宫术，刮出物未见明显异常。病理和细胞遗传学分析显示为三倍体胎儿（69,XXX），符合部分性葡萄胎妊娠。
妊娠20周前发生先兆子痫/子痫应促使进行临床评估，以排除潜在葡萄胎妊娠的可能性。
Zotero 插件