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[新生存活小牛的免疫球蛋白转移]

[Immunoglobulin transfer in the viable, newborn calf].

作者信息

Schäfer S, Wesenauer G, Arbeiter K

机构信息

Universitätsklinik für Geburtshilfe, Gynäkologie und Andrologie der Veterinärmedizinischen Universität Wien.

出版信息

Dtsch Tierarztl Wochenschr. 1998 Apr;105(4):153-7.

PMID:9618987
Abstract

Parturitions of 26 dairy-cows were observed and the viability of the newborn calves assessed. Immediately after birth as well as after the first and forth colostrum intake a blood probe was taken from the neonates and investigated for the following parameters: blood gas, blood picture, total-IG, concentrations of IGG1, IGM and IGE, total proteins and albumin. Before each feeding a colostrum sample was assayed for the same parameters with the exception of blood gas, blood picture and albumin. A transferindex (KLOBASA et al., 1994) was calculated to investigate the absorption of TP, IG, IGG1, IGM and IGE. In some of the blood samples there was no IGE detectable, even after colostrum intake. High individual differences were striking and blood concentrations were not related to the milk contents or the time until first feeding. The total proteins were strongly correlated to the serum concentrations of IGG1, but only in samples taken after first colostrum feeding. Vital calves showed the following tendency: colostrum intake of less than 1 l within the first 15 hours after birth and/or colostrum intake with TP-concentrations of 80 I.U./l was partly compensated by increased absorption of TP. 24 hours after birth serum-immunoglobulinconcentrations were 6-12 mg/ml; weight gain was normal and no calf became ill. In 60% of cases the transferindex for IGM was higher than for IGG1 or IGE.

摘要

观察了26头奶牛的分娩情况,并评估了新生犊牛的活力。在出生后以及首次和第四次摄入初乳后,立即从新生犊牛身上采集血样,并对以下参数进行检测:血气、血常规、总免疫球蛋白、IgG1、IgM和IgE的浓度、总蛋白和白蛋白。在每次喂食前,对初乳样本进行相同参数的检测,但不包括血气、血常规和白蛋白。计算转移指数(KLOBASA等人,1994年)以研究总蛋白、免疫球蛋白、IgG1、IgM和IgE的吸收情况。在一些血样中,即使在摄入初乳后也检测不到IgE。个体差异非常显著,血液浓度与乳汁含量或首次喂食前的时间无关。总蛋白与IgG1的血清浓度密切相关,但仅在首次摄入初乳后采集的样本中如此。存活的犊牛呈现出以下趋势:出生后15小时内初乳摄入量少于1升和/或初乳中总蛋白浓度为80国际单位/升时,总蛋白吸收增加可部分弥补这种情况。出生24小时后,血清免疫球蛋白浓度为6 - 12毫克/毫升;体重增加正常,没有犊牛生病。在60%的病例中,IgM的转移指数高于IgG1或IgE。

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