Torilin, a sesquiterpene from Torilis japonica, reverses multidrug-resistance in cancer cells.
作者信息
Kim S E, Kim Y H, Kim Y C, Lee J J
机构信息
Natural Product Biosynthesis RU., Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon, Korea.
出版信息
Planta Med. 1998 May;64(4):332-4. doi: 10.1055/s-2006-957445.
PMID:9619115
Abstract
A sesquiterpene compound reversing multidrug-resistance in cancer cells was isolated from the fruits of Torilis japonica and the structure was identified as torilin. Torilin potentiated the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells.
摘要
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