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腹主动脉瘤破裂的“所有患者均可参与”政策:如何改善治疗结果?

An "all comers" policy for ruptured abdominal aortic aneurysms: how can results be improved?

作者信息

Barry M C, Burke P E, Sheehan S, Leahy A, Broe P J, Bouchier-Hayes D J

机构信息

Department of Surgery, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin.

出版信息

Eur J Surg. 1998 Apr;164(4):263-70. doi: 10.1080/110241598750004481.

Abstract

OBJECTIVE

To review our experience of a non-selective policy for the treatment of ruptured abdominal aortic aneurysm to see if the policy was justified, and to identify any preoperative risk factors that adversely influenced outcome.

DESIGN

Retrospective study.

SETTING

Teaching hospital, Republic of Ireland.

SUBJECTS

258 patients admitted with abdominal aortic aneurysms between January 1982 and December 1993.

INTERVENTIONS

Definitive surgical treatment.

MAIN OUTCOME MEASURES

Morbidity, mortality, and risk factors.

RESULTS

In-hospital mortality for all patients was 43% (110/258). Overall, women did worse than men (28/44, 64%, died, compared with 96/214, 45%, p=0.03). The mortality among patients over the age of 80 (23/45, 51%) was not significantly different from that among younger patients (97/202, 48%). Blood pressure, platelet count, and haemoglobin concentration were all significantly lower preoperatively among those who died (p < 0.05).

CONCLUSIONS

Age alone cannot be used to justify witholding definitive surgical treatment. Treatment should be aimed towards reversing haematological and haemodynamic abnormalities preoperatively to try to improve outcome.

摘要

目的

回顾我们对腹主动脉瘤破裂采用非选择性治疗策略的经验,以判断该策略是否合理,并确定任何对预后有不利影响的术前危险因素。

设计

回顾性研究。

地点

爱尔兰共和国的教学医院。

研究对象

1982年1月至1993年12月期间收治的258例腹主动脉瘤患者。

干预措施

确定性手术治疗。

主要观察指标

发病率、死亡率和危险因素。

结果

所有患者的院内死亡率为43%(110/258)。总体而言,女性的情况比男性更差(28/44,64%死亡,而男性为96/214,45%,p=0.03)。80岁以上患者的死亡率(23/45,51%)与年轻患者(97/202,48%)相比无显著差异。死亡患者术前的血压、血小板计数和血红蛋白浓度均显著更低(p<0.05)。

结论

不能仅以年龄为由放弃确定性手术治疗。治疗应旨在术前纠正血液学和血流动力学异常,以试图改善预后。

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