中华大蟾蜍胰腺内分泌细胞：免疫细胞化学与超微结构
Pancreatic endocrine cells in Bufo bufo: immunocytochemistry and ultrastructure.
作者信息
Accordi F, Bracci M A, Ventola F
机构信息
Dipartimento di Biologia Animale e dell'Uomo, Università La Sapienza, Rome, Italy.
出版信息
J Anat. 1998 Feb;192 ( Pt 2)(Pt 2):195-202. doi: 10.1046/j.1469-7580.1998.19220195.x.
The endocrine pancreas of the toad consists of rounded islets of various sizes embedded in the exocrine tissue. Isolated cells are also present. At least 4 types of endocrine cell are distinguishable by shape, size and electrondensity of the secretory granules as well as by their immunoreactivity with different antisera: insulin, somatostatin, pancreatic polypeptide, and glucagon cells. Insulin cells can be divided into 2 types according to their cytoplasmic electrondensity. Colocalisation of different hormones in the same cell is rarely observed. The close contact between endocrine and exocrine cells and the scarcity of nerve supply is indicative of a paracrine control of hormone secretion.
蟾蜍的内分泌胰腺由嵌入外分泌组织中的各种大小的圆形胰岛组成。也存在孤立的细胞。至少有4种内分泌细胞可通过分泌颗粒的形状、大小、电子密度以及它们与不同抗血清的免疫反应性来区分：胰岛素、生长抑素、胰多肽和胰高血糖素细胞。胰岛素细胞可根据其细胞质电子密度分为2种类型。很少观察到同一细胞中不同激素的共定位。内分泌细胞与外分泌细胞之间的紧密接触以及神经供应的稀少表明激素分泌受旁分泌控制。
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