Giuseppetti G M, Baldassarre S, Marconi E
Institute of Diagnostic Semiology and Instrumental Therapy, University of Ancona, Italy.
Eur J Radiol. 1998 May;27 Suppl 2:S254-8. doi: 10.1016/s0720-048x(98)00076-x.
The authors report the results obtained with color Doppler sonography in the study of breast conditions. Color Doppler allows to detect the following main features in breast conditions: the presence of blood flow, vessel arrangement, vascularization extent, the number of vascular poles. To investigate slow flows, it is better to use low PRF values (not above 1 KHz) and low filters, while amplification should be set immediately above the system's noise threshold; the size of color Doppler box should be adjusted as small as possible to maximize sensitivity and minimize flash artifacts. In May 1992 to September 1997, 252 patients with solid breast masses were examined with mammography, B-mode, color Doppler and power Doppler sonography (only 57 cases). We identified histologically (176 cases) or cytologically (77 cases) 141 carcinomas and 112 benign solid lesions. The diameter of the 141 carcinomas ranged 0.4-4 cm (mean 1.7), while the diameter of benign lesions ranged 0.7-3 cm (mean 1.5). The malignancy pattern was characterized by hypervascularity (92.9%), irregular and abundant (54.2%) vascularization and more than one vascular pole. Benign lesions were avascular (43.4%) with poor and peripheral vascularity (90%) and mostly showed only one vascular pole. The avascular cancers (10 cases) were three mucoid, five in situ and two small (0.7 and 0.9 cm) invasive ductal carcinomas. The six benign lesions with irregular and abundant vascularization and more than one vascular pole were proved to be two proliferating and three juvenile fibroadenomas and one phylloid tumor. These results are encouraging and suggest that this technique can be a useful adjunct to mammography and sonography in the differential, diagnosis of breast nodules.
作者报告了彩色多普勒超声检查在乳腺疾病研究中获得的结果。彩色多普勒能够检测乳腺疾病中的以下主要特征:血流的存在、血管排列、血管化程度、血管极数量。为了研究缓慢血流,最好使用低脉冲重复频率值(不高于1千赫兹)和低滤波器,同时增益应设置在刚好高于系统噪声阈值的位置;彩色多普勒取样框的大小应尽可能调小,以提高灵敏度并减少闪烁伪像。1992年5月至1997年9月,对252例乳腺实性肿块患者进行了乳腺X线摄影、B超、彩色多普勒和能量多普勒超声检查(仅57例)。我们通过组织学(176例)或细胞学(77例)鉴定出141例癌和112例良性实性病变。141例癌的直径范围为0.4 - 4厘米(平均1.7厘米),而良性病变的直径范围为0.7 - 3厘米(平均1.5厘米)。恶性病变的特征为血管增多(92.9%)、血管化不规则且丰富(54.2%)以及不止一个血管极。良性病变无血管(43.4%),血管化差且位于周边(90%),大多仅显示一个血管极。无血管的癌(10例)包括3例黏液癌、5例原位癌和2例小的(0.7厘米和0.9厘米)浸润性导管癌。6例血管化不规则且丰富以及不止一个血管极的良性病变被证实为2例增生性和3例幼年性纤维腺瘤以及1例叶状肿瘤。这些结果令人鼓舞,表明该技术在乳腺结节的鉴别诊断中可作为乳腺X线摄影和超声检查的有用辅助手段。