Andros G J, Hatch D A, Walter J S, Wheeler J S, Schlehahn L, Damaser M S
Department of Urology, Loyola University Medical Center, Maywood, Illinois, USA.
J Urol. 1998 Aug;160(2):518-21.
We evaluate a pressure gauge used at home for patients with myelomeningocele on clean intermittent catheterization to provide a system for inexpensive frequent monitoring of bladder pressures.
Subjects with myelomeningocele using clean intermittent catheterization underwent cystometry in the laboratory. At home they obtained weekly volumes and bladder pressures before and after emptying. Home estimate of detrusor pressure was defined as full bladder pressure minus empty bladder pressure. Medication changes, subject position and urinary tract symptoms were noted.
A total of 11 subjects 10.5+/-7.3 years old have been enrolled and have made 16.7+/-12.6 weekly home bladder pressure and volume recordings in 4.7+/-3.1 months. Bladder capacities measured at home were 132+/-47% of cystometric capacities. At volumes of data overlap home full pressures (31+/-10 cm. water) were not statistically different from cystometric vesical pressures (25+/-9 cm. water). Home empty pressures (7+/-4 cm. water) were similar to cystometric abdominal pressures (14+/-8 cm. water). Home estimates of detrusor pressures (23+/-7 cm. water) magnified differences in full and empty pressures, and were significantly greater than cystometric detrusor pressures (11+/-11 cm. water). In 2 subjects significant increases in home full pressures occurred, which were associated with cessation of anticholinergic medication and infection.
Home monitoring of bladder pressure is a simple, inexpensive and accurate method of obtaining frequent bladder pressures in patients with myelomeningocele. These pressures are consistent over a large range of volumes and times, and could potentially be used to identify quickly changes in patient condition.
我们评估一种供脊髓脊膜膨出患者在家中进行清洁间歇性导尿时使用的压力计,以提供一种用于廉价且频繁监测膀胱压力的系统。
采用清洁间歇性导尿的脊髓脊膜膨出患者在实验室接受膀胱测压。在家中,他们在排尿前后每周获取尿量和膀胱压力。逼尿肌压力的家庭估计值定义为膀胱充盈时压力减去膀胱排空时压力。记录用药变化、受试者体位和尿路症状。
共纳入11名年龄为10.5±7.3岁的受试者,在4.7±3.1个月内进行了16.7±12.6次每周的家庭膀胱压力和尿量记录。在家中测量的膀胱容量为膀胱测压容量的132±47%。在数据重叠的尿量范围内,家庭膀胱充盈时压力(31±10厘米水柱)与膀胱测压膀胱压力(25±9厘米水柱)无统计学差异。家庭膀胱排空时压力(7±4厘米水柱)与膀胱测压腹压(14±8厘米水柱)相似。家庭逼尿肌压力估计值(23±7厘米水柱)放大了充盈和排空压力的差异,且显著高于膀胱测压逼尿肌压力(11±11厘米水柱)。2名受试者家庭膀胱充盈时压力显著升高,这与抗胆碱能药物停用和感染有关。
家庭膀胱压力监测是一种简单、廉价且准确的方法,可用于频繁获取脊髓脊膜膨出患者的膀胱压力。这些压力在较大的尿量范围和时间段内具有一致性,并有可能用于快速识别患者病情变化。