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环磷酰胺局部应用于胃黏膜局灶性溃疡性病变的鉴别诊断与治疗

[Local use of cyclophosphamide in differential diagnosis and treatment of focal ulcerative lesions of gastric mucosa].

作者信息

Butaev A V

出版信息

Klin Khir. 1998(4):38-9.

PMID:9695521
Abstract

Submucosal injection of cyclophosphamide (CPA) was applied in the ulcer disease and gastric cancer patients for rising of the endoscopical differential diagnosis efficacy. Under the influence of preparation the severity of inflammatory-proliferative changes in gastric wall have reduced, permitting to visualize the pathologically altered parts and to conduct a precise biopsy. The CPA application have promoted rapid arrest of algesic and dyspeptic syndromes and significant reduction of an ulcer healing term.

摘要

对溃疡病和胃癌患者进行环磷酰胺(CPA)黏膜下注射,以提高内镜鉴别诊断效果。在该制剂的作用下,胃壁炎症增生性改变的严重程度降低,有助于观察到病理改变部位并进行精确活检。应用CPA促使镇痛和消化不良综合征迅速缓解,并显著缩短溃疡愈合时间。

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