Llancapi P, Wagemann E, Namoncura M
Servicio de Dermatologia, Hospital Regional Guillermo Grant Benavente, Concepción, Chile.
Rev Med Chil. 1998 Apr;126(4):435-8.
Pellagra, caused by niacin deficiency, was described in 1730 by Casal in Spain and is specially frequent in alcoholics, subjects with malabsorption and mentally ill patients. We report three alcoholic patients (one female) aged 32, 57 and 26 years old, presenting with the typical desquamative and hyperpigmented lesions in exposed areas. One patient also had mental changes characterised by aggressiveness and clouding of consciousness. A diagnosis of pellagra was reached and treatment with nicotinic acid was started with good clinical response in all cases.
糙皮病由烟酸缺乏引起,1730年由西班牙的卡萨勒首次描述,在酗酒者、吸收不良者和精神病患者中尤为常见。我们报告了三名年龄分别为32岁、57岁和26岁的酗酒患者(一名女性),他们在暴露部位出现了典型的脱屑和色素沉着病变。一名患者还出现了以攻击性和意识模糊为特征的精神变化。诊断为糙皮病,并开始用烟酸治疗,所有病例临床反应良好。