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[在最先进的正电子发射断层扫描(PET)系统上对信噪比的研究:使用欧洲电工标准化委员会(CENELEC)全身模型进行的测量]

[Investigation of the signal-to-noise ratio on a state-of-the-art PET system: measurements with the EEC whole-body phantom].

作者信息

Jägel M, Adam L E, Bellemann M E, Zaers J, Trojan H, Rauschnabel K, Brix G

机构信息

Forschungsschwerpunkt Radiologische Diagnostik und Therapie, Deutsches Krebsforschungszentrum, Heidelberg, Deutschland.

出版信息

Nuklearmedizin. 1998 Aug;37(5):171-6.

PMID:9728344
Abstract

AIM

The spatial resolution of PET scanners can be improved by using smaller detector elements. This approach, however, results in poorer counting statistics of the reconstructed images. Therefore, the aim of this study was to investigate the influence of different acquisition parameters on the signal-to-noise ratio (SNR) and thus to optimize PET image quality.

METHODS

The experiments were performed with the latest-generation whole-body PET system (ECAT Exact HR+, Siemens/CTI) using the standard 2D and 3D data acquisition parameters recommended by the manufacturer. The EEC whole-body phantom with different inserts was used to simulate patient examinations of the thorax. Emission and transmission scans were acquired with varying numbers of events and at different settings of the lower level energy discriminator. The influence of the number of counts on the SNR was parameterized using a simple model function.

RESULTS

For count rates frequently encountered in clinical PET studies, the emission scan has a stronger influence on the SNR in the reconstructed image than the transmission scan. The SNR can be improved by using a higher setting of the lower energy level provided that the total number of counts is kept constant. Based on the established model function, the relative duration of the emission scan with respect to the total acquisition time was optimized, yielding a value of about 75% for both the 2D and 3D mode.

CONCLUSION

The presented phenomenological approach can readily be employed to optimize the SNR and thus the quality of PET images acquired at different scanners or with different examination protocols.

摘要

目的

通过使用更小的探测器元件可提高正电子发射断层扫描(PET)扫描仪的空间分辨率。然而,这种方法会导致重建图像的计数统计结果变差。因此,本研究的目的是调查不同采集参数对信噪比(SNR)的影响,从而优化PET图像质量。

方法

使用最新一代全身PET系统(ECAT Exact HR +,西门子/CTI)按照制造商推荐的标准2D和3D数据采集参数进行实验。使用带有不同插入物的EEC全身体模来模拟胸部的患者检查。发射扫描和透射扫描在不同的事件数量以及较低能量鉴别器的不同设置下进行采集。使用一个简单的模型函数对计数数量对SNR的影响进行参数化。

结果

对于临床PET研究中经常遇到的计数率,重建图像中的发射扫描对SNR的影响比透射扫描更强。如果总计数数量保持恒定,通过使用更高的较低能量水平设置可提高SNR。基于已建立的模型函数,优化了发射扫描相对于总采集时间的相对持续时间,在2D和3D模式下均得出约75%的值。

结论

所提出的现象学方法可轻松用于优化SNR,进而优化在不同扫描仪或使用不同检查方案获取的PET图像的质量。

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