Kramer S, Nolte I, Albrecht J, Klein A, Busse L, Farlopoulos S
Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.
Berl Munch Tierarztl Wochenschr. 1998 Jul-Aug;111(7-8):285-90.
Buprenorphine was used as a post-operative analgesic drug in 40 dogs and 30 cats. The analgesic properties of buprenorphine failed in 20% (dogs) respectively 23.3% (cats) of the cases even after high doses of 0.1 mg/kg in dogs and 0.01 mg/kg in cats. The unsatisfactory results were seen in fracture-patients with a concurrent severe tissue damage. Side effects even after high doses were of no clinical relevance.
丁丙诺啡被用作40只犬和30只猫的术后镇痛药。即使在犬中给予高剂量0.1mg/kg、猫中给予0.01mg/kg后,丁丙诺啡的镇痛特性仍分别在20%(犬)和23.3%(猫)的病例中失效。在伴有严重组织损伤的骨折患者中观察到了不尽人意的结果。即使给予高剂量,副作用也无临床相关性。