Suppr超能文献

[生命最初几年的复发性喘息性支气管炎:一项为期3年的随访]

[Recurrent asthmatic bronchitis in the first years of life: a 3-year follow-up].

作者信息

Brigante E, Cirillo G, Aurelio G, Nocerino G, Carbone M T, de Seta L

机构信息

IV Divisione di Pediatria, Ospedale Materno-Infantile SS. Annunziata, Napoli, Italia.

出版信息

Pediatr Med Chir. 1998 May-Jun;20(3):205-8.

PMID:9744014
Abstract

The natural history of asthma is not well known; its origin may go back to just after the birth. The aims of this study are: 1) studying the evolution of the symptomatology of a group of children suffering from recurrent asthmatic bronchitis of a moderate-severe level in the first two years of life; 2) inquiring some risk factors conditioning the evolution of it. One hundred children, aged from 16.6 to 53.4 months, suffering from moderate to severe recurrent asthmatic bronchitis, have been checked at the follow-up at the Broncopneumologic and Allergic Pediatric Unit of the SS Annunziata Hospital (Naples). Among the 100 children checked, 25 have been dropped at the follow-up; the difference between the sample checked and the one dropped at the follow-up is not statistically relevant. Four are variables examined: age, allergic medical history, number of asthma episodes, breast feeding, association or not of atopic dermatitis. The evolution of the symptomatology has not been propitious, as, at the end of three years of analysis, 73.3% of the 5-year-old patients had still persistent asthma. The risk factors of asthma recurrence are: parents smoking habits with a relative risk of 18 times more in patients with disadvantageous evolution (R.R. = 18) and at a less measure the overcrowding of the bedroom (R.R. = 1.5). The age at the onset in of the symptomatology, the positive familiar medical history for allergic illness, the breast feeding and the atopic dermatitis have not resulted statistically different between the group with advantageous evolution and the one with disadvantageous outcome. Passive smoking is a very disadvantageous prognostic factor; it may contribute to the disadvantageous evolution of the moderate to severe asthmatic bronchitis in the early childhood towards the recurrent or chronic bronchial asthma of the late childhood.

摘要

哮喘的自然病史尚不明确;其起源可能追溯到出生后不久。本研究的目的是:1)研究一组在生命最初两年患有中度至重度复发性哮喘性支气管炎的儿童症状的演变;2)探究影响其演变的一些风险因素。100名年龄在16.6至53.4个月之间、患有中度至重度复发性哮喘性支气管炎的儿童,在那不勒斯圣安农齐亚塔医院的支气管肺科和变态反应儿科进行了随访检查。在接受检查的100名儿童中,有25名在随访时退出;接受检查的样本与随访时退出的样本之间的差异无统计学意义。检查了四个变量:年龄、过敏病史、哮喘发作次数、母乳喂养、是否伴有特应性皮炎。症状的演变并不乐观,因为在三年的分析结束时,5岁患者中有73.3%仍患有持续性哮喘。哮喘复发的风险因素有:父母的吸烟习惯,病情演变不利的患者相对风险高18倍(相对风险=18),其次是卧室过度拥挤(相对风险=1.5)。症状出现时的年龄、家族过敏疾病阳性病史、母乳喂养和特应性皮炎在病情演变有利组和病情演变不利组之间没有统计学差异。被动吸烟是一个非常不利的预后因素;它可能导致幼儿期中度至重度哮喘性支气管炎向儿童后期复发性或慢性支气管哮喘的不利演变。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验