Dejin-Karlsson E, Hanson B S, Ostergren P O, Sjöberg N O, Marsal K
Department of Community Medicine, Malmö University Hospital, Sweden.
Am J Public Health. 1998 Oct;88(10):1523-7. doi: 10.2105/ajph.88.10.1523.
This study tested the hypothesis that women who deliver small-for-gestational-age infants are more often exposed to passive smoking at home or at work.
Among a 1-year cohort of nulliparous women in the city of Malmö, Sweden 872 (87.7%) women completed a questionnaire during their first prenatal visit. The study was carried out among women whose pregnancies resulted in a singleton live birth (n = 826), 6.7% of infants were classified as small for their gestational age.
Passive smoking in early pregnancy was shown to double a woman's risk of delivering a small-for-gestational-age infant, independent of potential confounding factors such as age, height, weight, nationality, educational level, and the mother's own active smoking (odds ratio [OR] = 2.7). A stratified analysis indicated interactional effects of maternal smoking and passive smoking on relative small-for-gestational-age risk.
Based on an attributable risk estimate, a considerable reduction in the incidence of small-for-gestational-age births could be reached if pregnant women were not exposed to passive smoking.
本研究检验了以下假设，即分娩小于胎龄儿的女性在家庭或工作场所更常接触被动吸烟。
在瑞典马尔默市一组为期1年的初产妇队列中，872名（87.7%）女性在首次产前检查时完成了一份问卷。该研究在妊娠结果为单胎活产的女性中进行（n = 826），6.7%的婴儿被归类为小于胎龄儿。
妊娠早期的被动吸烟被证明会使女性分娩小于胎龄儿的风险增加一倍，这与年龄、身高、体重、国籍、教育水平以及母亲自身主动吸烟等潜在混杂因素无关（优势比[OR] = 2.7）。分层分析表明，母亲吸烟和被动吸烟对相对小于胎龄儿风险存在交互作用。
基于归因风险估计，如果孕妇不接触被动吸烟，小于胎龄儿出生的发生率可能会大幅降低。
