Othmer E, Othmer J P, Othmer S C
Department of Psychiatry, University of Kansas Medical Center, Missouri, USA.
Psychiatr Clin North Am. 1998 Sep;21(3):517-66, v. doi: 10.1016/s0193-953x(05)70022-8.
Psychiatric disorders are viewed as brain disorders affecting five circuits of the brain: the brainstem, the hypothalamus, the motor striatum, the limbic system (ventral striatum), and the neocortex. This five-circuit model combines neuroscientific, psychopharmacologic, evolutionary, introspective, and behavioral data. The article presents a broad speculative overview of some brain functions and dysfunctions relevant for clinicians.