Scheepers B, Clough P, Pickles C
The David Lewis Centre for Epilepsy, Alderley Edge, Cheshire, UK.
Seizure. 1998 Oct;7(5):403-6. doi: 10.1016/s1059-1311(05)80010-x.
This paper reports the results of a population study designed to assess the standards of epilepsy care within a geographical population in relation to diagnosis, seizure management and quality of life. One of the findings was the unexpectedly high frequency of the misdiagnosis of epilepsy. Forty-nine of 214 patients with a primary diagnosis of epilepsy were subsequently found to have been misdiagnosed following a specialist review and investigations. All except two have been withdrawn from antiepileptic medication. The diagnosis of epilepsy was disputed in a further 26 patients. Of the 49 patients, 20 were found to have cardiovascular or cerebrovascular pathology. Seven had only ever experienced a single seizure and a further 10 were found to have underlying psychopathology. Such observations support the view that epilepsy is frequently misdiagnosed and this paper discusses some of the implications of misdiagnosis.
本文报告了一项旨在评估某一地理区域内癫痫护理在诊断、发作管理及生活质量方面标准的人群研究结果。其中一项发现是癫痫误诊的频率出人意料地高。在214例初步诊断为癫痫的患者中,49例在经过专家复查和检查后被发现误诊。除2例患者外,其余患者均已停用抗癫痫药物。另有26例患者的癫痫诊断存在争议。在这49例患者中,20例被发现患有心血管或脑血管疾病。7例仅经历过一次发作,另有10例被发现存在潜在精神病理学问题。这些观察结果支持了癫痫常被误诊这一观点,本文讨论了误诊的一些影响。