Fénichel P
Groupe de Recherche sur l'Interaction gamétique, CJF-INSERM 95-04, Faculté de Médecine, Nice.
Contracept Fertil Sex. 1998 Jul-Aug;26(7-8):549-53.
Fertilization includes sperm-oocyte recognition, adhesion, binding, fusion and egg activation. Integrin receptors which are adhesion molecules are expressed on unfertilized oocytes. By comparing to several cell-cell interactions such as lymphocyte activation, viral fusion, bacterial infection or macrophage phagocytosis, potential sperm ligands have been identified.
受精包括精子-卵母细胞识别、黏附、结合、融合及卵子激活。整合素受体作为黏附分子,在未受精的卵母细胞上表达。通过与淋巴细胞激活、病毒融合、细菌感染或巨噬细胞吞噬等几种细胞间相互作用进行比较,已鉴定出潜在的精子配体。