Fortney J, Booth B, Zhang M, Humphrey J, Wiseman E
Veterans Affairs Medical Center, Centers for Mental Healthcare Research, Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock 72114, USA.
J Stud Alcohol. 1998 Nov;59(6):690-7. doi: 10.15288/jsa.1998.59.690.
The purpose of this research was to control for self-selection bias in the evaluation of Alcoholics Anonymous (AA) as aftercare treatment. Observational studies of alcoholism aftercare treatment are subject to selection bias whenever the self-selection process results in important differences in unobserved casemix dimensions between treatment groups.
The sample included 118 male veterans discharged from inpatient alcohol treatment, 85% of whom were followed-up at 3 months. Drinking outcomes were measured by self-reported abstinence in the third month after discharge. The aftercare treatment effect of AA was estimated using standard logistic regression analysis and instrumental variables analysis. Instruments included the subject's ability to drive oneself to AA meetings and the presence/absence of an AA meeting in the subject's town of residence. A Hausman exogeniety test was used to determine whether the standard logistic regression results were subject to self-selection bias.
Estimates from the standard logistic regression yielded a positive (OR = 3.7) and significant (p = .018) treatment effect for AA attendance. However, the instrumental variables analysis yielded a smaller (OR* = 1.7) and insignificant treatment effect estimate (p = .782). The Hausman exogeniety test indicated that the treatment effect estimate from the standard logistic regression was subject to significant self-selection bias (chi2 = 83.9, 1 df, p <.01).
The AA aftercare treatment effect observed in this sample was due to differences in unobserved casemix factors between the treatment groups. Results suggest that previous AA aftercare research may have also been subject to self-selection bias. Researchers of substance abuse outcomes should consider analyzing nonexperimental data using instrumental variables methodologies.
本研究旨在控制在评估匿名戒酒互助会(AA)作为后续护理治疗时的自我选择偏差。只要自我选择过程导致治疗组之间在未观察到的病例组合维度上存在重要差异,酗酒后续护理治疗的观察性研究就会受到选择偏差的影响。
样本包括118名从住院酒精治疗中出院的男性退伍军人,其中85%在3个月时接受了随访。饮酒结果通过出院后第三个月的自我报告戒酒情况来衡量。使用标准逻辑回归分析和工具变量分析来估计AA的后续护理治疗效果。工具包括受试者自行开车前往AA会议的能力以及受试者居住城镇中是否存在AA会议。使用豪斯曼外生性检验来确定标准逻辑回归结果是否受到自我选择偏差的影响。
标准逻辑回归的估计结果显示,参加AA有积极的(OR = 3.7)且显著的(p = 0.018)治疗效果。然而,工具变量分析得出的治疗效果估计值较小(OR* = 1.7)且不显著(p = 0.782)。豪斯曼外生性检验表明,标准逻辑回归的治疗效果估计受到显著的自我选择偏差影响(卡方 = 83.9,1自由度,p < 0.01)。
本样本中观察到的AA后续护理治疗效果是由于治疗组之间未观察到的病例组合因素的差异。结果表明,先前关于AA后续护理治疗的研究可能也受到了自我选择偏差的影响。药物滥用结果的研究人员应考虑使用工具变量方法分析非实验数据。