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[与结肠息肉病相关的多发性毛发上皮瘤]

[Multiple trichodiscomas associated with colonic polyposis].

作者信息

Le Guyadec T, Dufau J P, Poulain J F, Vaylet F, Grossin M, Lanternier G

机构信息

Service de Dermatologie, Hôpital d'Instruction des Armées Percy, Clamart.

出版信息

Ann Dermatol Venereol. 1998 Oct;125(10):717-9.

PMID:9835964
Abstract

BACKGROUND

Trichodiscoma is an uncommon benign tumor of the pilosebaceous system.

CASE REPORT

An 83-year-old man had a past history of adenomatous polyps of the colon. The subject's brother had died from cancer of the colon. Over the past 4 years, the patient had developed approximately 30 small asymptomatic papulonodular tumors on the trunk. Skin biopsy demonstrated trichodiscomas.

DISCUSSION

Together with fibrofolliculomas and perifollicular fibromas, trichodiscomas are benign tumors of the pilosebaceous system. These different tumors may occur simultaneously as in Birt-Hogg-Dubé syndrome which associates trichodiscoma and familial colonic polyposis. This combination has only been reported in Birt-Hogg-Dubé syndrome or with perifollicular fibromas.

CONCLUSION

This case suggests that patients with hamartomas of the pilosebaceous system should undergo explorations in search for digestive tract polyposis.

摘要

背景

毛发上皮瘤是一种罕见的皮脂腺系统良性肿瘤。

病例报告

一名83岁男性有结肠腺瘤性息肉病史。该患者的兄弟死于结肠癌。在过去4年里,患者躯干上出现了约30个无症状的小丘疹结节性肿瘤。皮肤活检显示为毛发上皮瘤。

讨论

毛发上皮瘤与纤维毛囊瘤和毛囊周围纤维瘤一样,是皮脂腺系统的良性肿瘤。这些不同的肿瘤可能同时出现,如在Birt-Hogg-Dubé综合征中,该综合征伴有毛发上皮瘤和家族性结肠息肉病。这种组合仅在Birt-Hogg-Dubé综合征或伴有毛囊周围纤维瘤时被报道过。

结论

该病例提示,患有皮脂腺系统错构瘤的患者应进行检查以寻找消化道息肉病。

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