Bednarík J, Kadanka Z, Vohánka S, Novotný O, Surelová D, Filipovicová D, Prokes B
Department of Neurology, Faculty Hospital Brno, Czech Republic.
Eur Spine J. 1998;7(6):493-500. doi: 10.1007/s005860050113.
Previous studies have yielded conflicting data concerning the value of evoked potential parameters in the assessment of clinical relevance of cervical cord compression in clinically "silent" cases. The aim of this study was to assess the value of somatosensory (SEP) and motor evoked potentials (MEP) in the evaluation and prediction of the clinical course, by means of a 2-year follow-up prospective electrophysiological and clinical study performed in patients with clinically "silent" spondylotic cervical cord compression. Thirty patients with MR signs of spondylotic cervical cord compression but without clinical signs of myelopathy were evaluated clinically and using SEPs and MEPs during a 2-year period. The results of the study showed that SEPs and MEPs documented subclinical involvement of cervical cord in 50% of patients with clinically "silent" spondylotic cervical cord compression. During the 2-year period clinical signs of cervical myelopathy were observed in one-third of patients with entry EP abnormality in comparison with no patients with normal EP tests. Combined SEPs and MEPs proved to be a valuable tool in the assessment of the functional relevance of subclinical spondylotic cervical cord compression. Normal EP findings predict a favourable 2-year clinical outcome.
以往的研究在评估临床上“无症状”病例中颈髓压迫的临床相关性时,关于诱发电位参数的价值得出了相互矛盾的数据。本研究的目的是,通过对临床上“无症状”的脊髓型颈椎病患者进行为期2年的前瞻性电生理和临床研究,评估体感诱发电位(SEP)和运动诱发电位(MEP)在评估和预测临床病程中的价值。对30例有脊髓型颈椎病MR征象但无脊髓病临床体征的患者,在2年期间进行了临床评估,并使用SEP和MEP进行检查。研究结果表明,在临床上“无症状”的脊髓型颈椎病患者中,SEP和MEP显示50%的患者存在颈髓亚临床受累。在这2年期间,与EP检查正常的患者相比,三分之一EP检查异常的患者出现了脊髓病的临床体征。联合使用SEP和MEP被证明是评估亚临床脊髓型颈椎病功能相关性的一个有价值的工具。EP检查结果正常预示着2年的临床预后良好。