Whitecloud T S, Castro F P, Brinker M R, Hartzog C W, Ricciardi J E, Hill C
Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA.
J Spinal Disord. 1998 Dec;11(6):479-86.
Thirty-five consecutive patients were evaluated at an average follow-up time of 20 months after circumferential lumbar spinal fusion. All patients had degenerative conditions of the lumbar spine and same-day anterior spinal fusion by using titanium cages packed with autograft bone and posterior instrumentation combined with a posterolateral autogenous bone graft. The purpose of this study was to determine whether anterior titanium cage placement and posterior instrumentation with autologous bone graft was a safe and efficacious procedure in patients with degenerative disease of the lumbar spine. Fusion rates, complications, pain relief, medication use, and work status were specifically analyzed. Although previous reports documented the use of this technique for trauma and tumor cases, few studies assessed clinical and radiographic results in patients with degenerative conditions of the lumbar spine. Plain radiographs were used to determine spinal fusion at each spinal level. All patients were administered preoperative and postoperative questionnaires regarding three specific clinical-outcome parameters. These consisted of pain level, medication use, and work status. Intraoperative and postoperative complications were also documented. Radiographic results showed that 61 (97%) of 63 lumbar levels undergoing an arthrodesis procedure fused either anteriorly, posteriorly, or both. Of the 35 patients in this series, 33 (94%) fused at all levels, and two did not. Substantial pain relief was reported in 46% of all patients. Thirteen (37%) patients had one or more surgical complications. Circumferential spinal fusion in patients with degenerative etiologies yields excellent radiographic fusion rates and good pain relief. The procedure is technically demanding and is associated with a high rate of complications.
对35例连续患者进行了评估,平均随访时间为腰椎环形融合术后20个月。所有患者均患有腰椎退行性疾病,并在同一天接受了前路脊柱融合术,使用填充自体骨的钛笼和后路器械固定,并结合后外侧自体骨移植。本研究的目的是确定前路钛笼置入和后路器械固定联合自体骨移植在腰椎退行性疾病患者中是否是一种安全有效的手术方法。具体分析了融合率、并发症、疼痛缓解情况、药物使用情况和工作状态。尽管先前的报告记录了该技术在创伤和肿瘤病例中的应用,但很少有研究评估腰椎退行性疾病患者的临床和影像学结果。通过普通X线片确定每个脊柱节段的脊柱融合情况。所有患者均接受了术前和术后关于三个特定临床结局参数的问卷调查。这些参数包括疼痛程度、药物使用情况和工作状态。还记录了术中及术后并发症。影像学结果显示,63个接受融合手术的腰椎节段中有61个(97%)在前路、后路或前后路均实现了融合。在本系列的35例患者中,33例(94%)所有节段均实现了融合,2例未融合。46%的患者报告疼痛得到了显著缓解。13例(37%)患者发生了一种或多种手术并发症。病因退行性的患者进行环形脊柱融合术可获得优异的影像学融合率和良好的疼痛缓解效果。该手术技术要求高,且并发症发生率高。