双侧隐睾症与10号染色体长臂末端缺失相关。
Bilateral cryptorchidism associated with terminal deletion of 10q.
作者信息
Suzuki Y, Sasagawa I, Nakada T, Onmura Y
机构信息
Department of Urology, Yamagata University School of Medicine, Yamagata, Japan.
出版信息
Urol Int. 1998;61(3):186-7. doi: 10.1159/000030321.
PMID:9933844
Abstract
We report on an infant with terminal deletion of 10q (del10q26.11) presenting with bilateral cryptorchidism. Of 9 males previously reported with terminal deletion of 10q, 1 had an intersex phenotype, and the others all had combinations of cryptorchidism, micropenis, and hypospadias. Terminal deletion of 10q appears to include some genes indispensable for normal male genital development.
摘要
我们报告了一名患有10号染色体长臂末端缺失（del10q26.11）并伴有双侧隐睾症的婴儿。在先前报道的9例患有10号染色体长臂末端缺失的男性中，1例具有两性畸形表型，其他所有病例均伴有隐睾症、小阴茎和尿道下裂。10号染色体长臂末端缺失似乎包含一些对正常男性生殖器发育不可或缺的基因。
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