[灵菌红素对类鼻疽中溶菌酶活性的影响]

[Effect of prodigiosin on the lysozyme activity in melioidosis].

作者信息

Morozova E Ia, Efimtseva E P, Ermol'eva Z V

出版信息

Antibiotiki. 1976 May;21(5):444-6.

Abstract

Decreased lysozyme activity was observed under conditions of melioidosis intoxication in rats induced by intraperitoneal administration of an acetone-killed 3-day culture of the bacterial mass of the melioidosis causative agent. When prodigiozan was administered 48 hours by the 4th day which was indicative of prodigiozan activation of the factors of the microbial non-specific resistance.

摘要

在通过腹腔注射由类鼻疽病原体细菌团块的丙酮灭活3天培养物诱导的大鼠类鼻疽中毒条件下，观察到溶菌酶活性降低。当在第4天前48小时给予灵菌红素时，这表明灵菌红素激活了微生物非特异性抗性因子。