静脉注射免疫球蛋白治疗急性播散性脑脊髓炎。
Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin.
作者信息
Sahlas D J, Miller S P, Guerin M, Veilleux M, Francis G
机构信息
McGill University Health Centre, the Montreal Neurological Hospital, Québec, Canada.
出版信息
Neurology. 2000 Mar 28;54(6):1370-2. doi: 10.1212/wnl.54.6.1370.
Acute disseminated encephalomyelitis (ADEM) is a presumed immune-mediated, demyelinating disease of the CNS for which the standard treatment is high-dose steroids. We describe two patients with ADEM in whom treatment with IV methylprednisolone coincided with deterioration in their clinical status. They were subsequently treated with IV immunoglobulin and exhibited dramatic clinical improvement, with return to their previous level of functioning.
急性播散性脑脊髓炎（ADEM）被认为是一种中枢神经系统的免疫介导性脱髓鞘疾病，其标准治疗方法是大剂量使用类固醇。我们描述了两名患有ADEM的患者，他们接受静脉注射甲基强的松龙治疗时临床状况却恶化。随后他们接受了静脉注射免疫球蛋白治疗，临床症状显著改善，恢复到了之前的功能水平。
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