The outcome of dothiepin treatment in 1,900 depressed patients.

One thousand, nine hundred and sixty-five depressed patients took part in a multicentre study of dothiepin hydrochloride, which involved 392 doctors. The results indicated that a large percentage of patients improved as measured by all the assessments and no serious or adverse effects were encountered. A good correlation was seen between the global scale and the Rockliff depression scale; and also between the final mean Rockliff score and the number of patients stopping therapy due to recovery, and continuing treatment until recovery, at the final assessment.