衰老:新靶点,新功能。

Aging: new targets, new functions.

作者信息

Patterson Garth I

机构信息

Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.

出版信息

Curr Biol. 2003 Apr 1;13(7):R279-81. doi: 10.1016/s0960-9822(03)00201-x.

Abstract

The DAF-16 transcription factor controls aging in C. elegans as part of an insulin-like signaling pathway. Identification of a target of DAF-16 has opened a new window into the aging process.

摘要

DAF-16转录因子作为胰岛素样信号通路的一部分,调控线虫的衰老过程。对DAF-16靶标的鉴定为衰老过程打开了一扇新的窗口。

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