衰老:新靶点,新功能。
Aging: new targets, new functions.
作者信息
Patterson Garth I
机构信息
Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.
出版信息
Curr Biol. 2003 Apr 1;13(7):R279-81. doi: 10.1016/s0960-9822(03)00201-x.
Abstract
The DAF-16 transcription factor controls aging in C. elegans as part of an insulin-like signaling pathway. Identification of a target of DAF-16 has opened a new window into the aging process.
摘要
DAF-16转录因子作为胰岛素样信号通路的一部分,调控线虫的衰老过程。对DAF-16靶标的鉴定为衰老过程打开了一扇新的窗口。