近视“流行”的证据。

Evidence for an "epidemic" of myopia.

作者信息

Park D J J, Congdon N G

机构信息

Johns Hopkins University Schools of Medicine, Baltimore, USA.

出版信息

Ann Acad Med Singap. 2004 Jan;33(1):21-6.

DOI:
Abstract

INTRODUCTION

It has been widely suggested that the prevalence of myopia is growing worldwide, and that the increases observed in East Asia, in particular, are sufficiently severe as to warrant the term "epidemic". Data in favour of a cohort effect in myopia prevalence are reviewed, with attention to significant shortcomings in the quality of available evidence. Additional factors contributing to myopia prevalence, including near work, genetics and socioeconomic status, are detailed.

MATERIALS AND METHODS

Medline search of articles regarding myopia prevalence, trends and mechanisms.

RESULTS

Age-related changes in myopia prevalence (increase during childhood, and regression in the fifth and sixth decades) are discussed as an alternative explanation for cross-sectional patterns in myopia prevalence. There have only been a handful of studies that have examined the relative contribution of longitudinal changes in refraction over life and birth cohort differences on age-specific myopia prevalence as measured in cross-sectional studies. Available data suggest that both longitudinal changes and cohort effects may be present, and that their relative contribution may differ in different racial groups.

CONCLUSIONS

In view of the relatively weak evidence in favour of a large cohort effect for myopia in East Asia, and the even greater lack of evidence for increased prevalence of secondary ocular pathology, there appears to be inadequate support for large-scale interventions to prevent or delay myopia at the present time.

摘要

引言

人们普遍认为,全球近视患病率正在上升,尤其是在东亚地区,其增长幅度之大足以被称为“流行”。本文回顾了支持近视患病率存在队列效应的数据,并关注现有证据质量方面的重大缺陷。此外,还详细阐述了导致近视患病率上升的其他因素,包括近距离工作、遗传和社会经济地位。

材料与方法

通过医学文献数据库检索有关近视患病率、趋势和机制的文章。

结果

讨论了近视患病率与年龄相关的变化(儿童期增加,五、六十年代出现回退),以此作为对近视患病率横断面模式的另一种解释。仅有少数研究考察了一生中屈光不正的纵向变化和出生队列差异对横断面研究中特定年龄近视患病率的相对贡献。现有数据表明,纵向变化和队列效应可能都存在,且它们的相对贡献在不同种族群体中可能有所不同。

结论

鉴于支持东亚地区近视存在较大队列效应的证据相对薄弱,且关于继发性眼部病变患病率增加的证据更为匮乏,目前似乎没有足够的依据支持大规模干预措施来预防或延缓近视。

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