Kukla Piotr, Słowiak-Lewińska Teresa
Oddział Chorób Wewnetrznych z pododdziałem Kardiologii, Szpital Specjalistyczny im H. Klimontowicza, Gorlice, Poland.
Kardiol Pol. 2004 Apr;60(4):365-70; discussion 371.
Five patients with amiodarone-induced QT prolongation and torsade de pointes are described. Hypokalemia was present in three patients, marked bradycardia - in two, and T-wave alternans - also in two patients. Patients with negative T waves in precordial leads were at higher risk of ventricular fibrillation than the patients with positive T waves. Beta-blocker, lidocaine and, in two patients, tosylate bretylate were effective. All patients survived to hospital discharge, however, one patient died four months later.
本文描述了5例胺碘酮诱发QT间期延长和尖端扭转型室速的患者。3例患者存在低钾血症,2例有显著心动过缓,2例有T波电交替。胸前导联T波倒置的患者发生心室颤动的风险高于T波直立的患者。β受体阻滞剂、利多卡因以及2例患者使用的托西溴苄铵有效。所有患者均存活至出院,但有1例患者在4个月后死亡。