[胞二磷胆碱治疗大鼠低压缺氧的血流动力学、功能及生化效应]

[Hemodynamic, functional and biochemical effects of hypobaric hypoxia in rats treated with cytidine diphosphocholine].

作者信息

Boismare F, Le Poncin-Lafitte M, Rapin J R

出版信息

C R Seances Soc Biol Fil. 1978;172(4):651-8.

Abstract

Treatment with cytidine diphosphocholine (20 mg/kg i.p.) in rats induces, during acute hypoxia, a reduction of vegetative responses (no modification of cerebral blood flow), a protection of conditioned avoidance response and a stabilization of dopamine and noradrenaline cerebral levels.

摘要

用胞苷二磷酸胆碱（20毫克/千克腹腔注射）对大鼠进行治疗，在急性缺氧期间可诱导植物性反应降低（脑血流量无改变），保护条件性回避反应，并使大脑中多巴胺和去甲肾上腺素水平稳定。